MicroStrategy's Bitcoin holdings have surpassed 450,000 BTC after a $243 million investment during a market dip, totaling $28.2 billion at an average price of $62,691. This purchase coincided with a significant drop in Bitcoin exchange reserves, potentially signaling a price rally due to diminishing supply.Despite Bitcoin reaching a record high of over $100,000 in December 2024, macroeconomic factors, including strong US labor market data and concerns over the Federal Reserve's tightening monetary policy, have contributed to recent price declines. Other firms, like Semler Scientific, are also capitalizing on the dip, purchasing additional Bitcoin.